Motif ID: NFY{A,B,C}.p2

Z-value: 3.213


Transcription factors associated with NFY{A,B,C}.p2:

Gene SymbolEntrez IDGene Name
NFYA 4800 nuclear transcription factor Y, alpha
NFYB 4801 nuclear transcription factor Y, beta
NFYC 4802 nuclear transcription factor Y, gamma

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFYCchr1_+_409299930.693.4e-03Click!
NFYAchr6_+_411486650.381.5e-01Click!
NFYBchr12_-_103055924-0.029.3e-01Click!


Activity profile for motif NFY{A,B,C}.p2.

activity profile for motif NFY{A,B,C}.p2


Sorted Z-values histogram for motif NFY{A,B,C}.p2

Sorted Z-values for motif NFY{A,B,C}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFY{A,B,C}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_27669029 3.289 NM_152740
HIBADH
3-hydroxyisobutyrate dehydrogenase
chr19_-_4293718 3.247 STAP2
signal transducing adaptor family member 2
chr22_-_20419975 3.137 NM_013313
YPEL1
yippee-like 1 (Drosophila)
chr8_-_144762765 3.016 NM_023078
PYCRL
pyrroline-5-carboxylate reductase-like
chr17_-_35827568 2.847 NM_001067
TOP2A
topoisomerase (DNA) II alpha 170kDa
chr2_+_69995656 2.491 NM_002357
MXD1
MAX dimerization protein 1
chr6_-_31938572 2.469 NM_000434
NEU1
sialidase 1 (lysosomal sialidase)
chr1_+_110683467 2.456 NM_022768
RBM15
RNA binding motif protein 15
chr17_+_54587882 2.411 PRR11
proline rich 11
chr18_-_43711452 2.383 NM_001003652
NM_001135937
SMAD2

SMAD family member 2

chr1_+_210525397 2.371 PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr1_-_151910057 2.354 ILF2
interleukin enhancer binding factor 2, 45kDa
chr1_-_151910052 2.354 ILF2
interleukin enhancer binding factor 2, 45kDa
chr2_+_69995740 2.331 MXD1
MAX dimerization protein 1
chr1_-_151910080 2.330 ILF2
interleukin enhancer binding factor 2, 45kDa
chr1_-_151910041 2.307 ILF2
interleukin enhancer binding factor 2, 45kDa
chr19_-_59355246 2.299 NM_024316
LENG1
leukocyte receptor cluster (LRC) member 1
chr6_+_31903374 2.193 NM_005346
HSPA1A
HSPA1B
heat shock 70kDa protein 1A
heat shock 70kDa protein 1B
chrX_-_77037563 2.181 NM_032121
MAGT1
magnesium transporter 1
chr17_-_54587581 2.151 NM_001100595
NM_182620
SKA2

spindle and kinetochore associated complex subunit 2

chr19_-_60369731 2.131 NM_178837
C19orf51
chromosome 19 open reading frame 51
chr22_+_20326541 2.114 NM_022044
SDF2L1
stromal cell-derived factor 2-like 1
chr22_+_20326572 2.055 SDF2L1
stromal cell-derived factor 2-like 1
chr5_+_145807059 2.049 NM_001040006
NM_006706
TCERG1

transcription elongation regulator 1

chr19_+_60543032 2.047 NM_032701
SUV420H2
suppressor of variegation 4-20 homolog 2 (Drosophila)
chr19_-_14108400 2.035 NM_018154
ASF1B
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr1_+_28458546 1.989 NM_031459
SESN2
sestrin 2
chr15_+_96304911 1.971 NM_183376
ARRDC4
arrestin domain containing 4
chr22_-_21193037 1.950 ZNF280B
zinc finger protein 280B
chr19_+_50373842 1.927 NM_212550
BLOC1S3
biogenesis of lysosomal organelles complex-1, subunit 3
chr5_+_151131655 1.922 NM_005754
NM_198395
G3BP1

GTPase activating protein (SH3 domain) binding protein 1

chr17_+_54587641 1.920 NM_018304
PRR11
proline rich 11
chr22_+_20326591 1.918 SDF2L1
stromal cell-derived factor 2-like 1
chr16_-_2204776 1.916 NM_001042371
PGP
phosphoglycolate phosphatase
chr1_-_46370837 1.911 NM_003629
NM_001114172
PIK3R3

phosphoinositide-3-kinase, regulatory subunit 3 (gamma)

chr20_-_60415729 1.905 NM_031215
CABLES2
Cdk5 and Abl enzyme substrate 2
chr2_+_69995807 1.886 MXD1
MAX dimerization protein 1
chr5_+_151131676 1.884 G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr7_+_149707338 1.883 NM_173680
ZNF775
zinc finger protein 775
chr22_+_20326615 1.875 SDF2L1
stromal cell-derived factor 2-like 1
chr5_+_151131709 1.857 G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr5_+_151131707 1.850 G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr11_-_2677799 1.848 KCNQ1OT1
KCNQ1 overlapping transcript 1 (non-protein coding)
chr5_+_151131704 1.842 G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr17_-_54587306 1.824 SKA2
spindle and kinetochore associated complex subunit 2
chr1_-_151910098 1.811 NM_004515
ILF2
interleukin enhancer binding factor 2, 45kDa
chr17_+_43373887 1.793 NM_018129
PNPO
pyridoxamine 5'-phosphate oxidase
chr1_-_148936123 1.788 NM_018178
GOLPH3L
golgi phosphoprotein 3-like
chr6_-_31938530 1.768 NEU1
sialidase 1 (lysosomal sialidase)
chr1_+_210525490 1.753 NM_006243
PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr21_-_33774033 1.731 TMEM50B
transmembrane protein 50B
chr15_+_96304942 1.731 ARRDC4
arrestin domain containing 4
chr6_-_31890765 1.721 NM_005527
HSPA1L
heat shock 70kDa protein 1-like
chr22_+_36384647 1.681 NM_020315
PDXP
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr21_-_33774096 1.680 TMEM50B
transmembrane protein 50B
chr7_-_72114342 1.673 NM_001013739
STAG3L3
STAG3L2
STAG3L1
stromal antigen 3-like 3
stromal antigen 3-like 2
stromal antigen 3-like 1
chr22_-_20551937 1.619 MAPK1
mitogen-activated protein kinase 1
chr6_+_31891293 1.605 HSPA1A
heat shock 70kDa protein 1A
chr21_-_33774150 1.596 NM_006134
TMEM50B
transmembrane protein 50B
chr6_+_31891509 1.595 HSPA1A
HSPA1B
heat shock 70kDa protein 1A
heat shock 70kDa protein 1B
chr20_+_61967033 1.595 NM_003288
NM_199359
NM_199360
NM_199361
NM_199362
NM_199363
TPD52L2





tumor protein D52-like 2





chr9_-_127043169 1.594 HSPA5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr16_+_56327127 1.590 NM_005886
KATNB1
katanin p80 (WD repeat containing) subunit B 1
chr9_-_127043436 1.540 HSPA5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr6_+_31891259 1.540 NM_005345
HSPA1A
heat shock 70kDa protein 1A
chr11_+_63710206 1.540 STIP1
stress-induced-phosphoprotein 1
chr22_-_20551953 1.536 NM_002745
NM_138957
MAPK1

mitogen-activated protein kinase 1

chr22_-_21193504 1.528 NM_080764
ZNF280B
zinc finger protein 280B
chr1_-_109742020 1.525 NM_002959
SORT1
sortilin 1
chr1_-_226679648 1.509 NM_003493
HIST3H3
histone cluster 3, H3
chr1_-_23567084 1.489 NM_030634
ZNF436
zinc finger protein 436
chr9_+_130883199 1.488 NM_001135917
NM_020438
DOLPP1

dolichyl pyrophosphate phosphatase 1

chr19_-_14108267 1.485 ASF1B
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr9_-_127043455 1.479 NM_005347
HSPA5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr7_+_74826369 1.476 NM_001002840
NM_018991
STAG3L3
STAG3L2
STAG3L1

stromal antigen 3-like 3
stromal antigen 3-like 2
stromal antigen 3-like 1

chr1_-_159257486 1.476 F11R
F11 receptor
chr6_-_136613097 1.476 NM_001099286
NM_138419
FAM54A

family with sequence similarity 54, member A

chr2_-_73151894 1.466 SFXN5
sideroflexin 5
chr22_-_20551722 1.443 MAPK1
mitogen-activated protein kinase 1
chr7_+_100047660 1.425 NM_001040097
MOSPD3
motile sperm domain containing 3
chr7_-_100262971 1.406 NM_004444
EPHB4
EPH receptor B4
chr19_+_2928480 1.401 NM_001143986
NM_024760
TLE6

transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)

chr5_+_108112537 1.400 FER
fer (fps/fes related) tyrosine kinase
chr16_-_85908254 1.385 LOC100506581
hypothetical LOC100506581
chr11_+_63710242 1.358 STIP1
stress-induced-phosphoprotein 1
chr15_+_78139073 1.342 NM_019006
ZFAND6
zinc finger, AN1-type domain 6
chr19_+_18164989 1.323 NM_032683
MPV17L2
MPV17 mitochondrial membrane protein-like 2
chr1_+_110683580 1.316 RBM15
RNA binding motif protein 15
chr15_+_78139098 1.301 ZFAND6
zinc finger, AN1-type domain 6
chr9_+_132990760 1.290 NM_005085
NUP214
nucleoporin 214kDa
chr20_+_61967078 1.269 TPD52L2
tumor protein D52-like 2
chr9_+_132990834 1.265 NUP214
nucleoporin 214kDa
chr1_+_148726497 1.264 TARS2
threonyl-tRNA synthetase 2, mitochondrial (putative)
chr1_+_150029798 1.259


chr17_+_1566566 1.253 NM_001163673
NM_152348
WDR81

WD repeat domain 81

chr4_-_2233504 1.249 NM_006454
MXD4
MAX dimerization protein 4
chr16_-_65774904 1.236 KIAA0895L
KIAA0895-like
chr6_-_33493640 1.232 CUTA
cutA divalent cation tolerance homolog (E. coli)
chr1_+_6767968 1.231 NM_001195563
NM_015215
CAMTA1

calmodulin binding transcription activator 1

chr19_+_19035792 1.223 NM_178526
SLC25A42
solute carrier family 25, member 42
chr16_+_2419388 1.208 NM_001761
CCNF
cyclin F
chr14_-_22825148 1.197 NM_020834
HOMEZ
homeobox and leucine zipper encoding
chr17_+_71772875 1.190 NM_182565
FAM100B
family with sequence similarity 100, member B
chr1_-_180627512 1.190 GLUL
glutamate-ammonia ligase
chr1_+_110683586 1.183 RBM15
RNA binding motif protein 15
chr5_+_44844724 1.182 NM_016640
MRPS30
mitochondrial ribosomal protein S30
chr5_+_122875691 1.178 NM_001031812
NM_001044722
NM_001044723
NM_004384
CSNK1G3



casein kinase 1, gamma 3



chr2_-_73152323 1.177 NM_144579
SFXN5
sideroflexin 5
chr10_+_62208094 1.173 NM_001170406
NM_001170407
NM_001786
NM_033379
CDK1



cyclin-dependent kinase 1



chr10_+_70418482 1.165 NM_015634
KIAA1279
KIAA1279
chr1_-_28113540 1.162 RPA2
replication protein A2, 32kDa
chr17_-_77411803 1.162 NM_000918
P4HB
prolyl 4-hydroxylase, beta polypeptide
chr2_-_136005238 1.161 NM_032143
ZRANB3
zinc finger, RAN-binding domain containing 3
chr9_-_139604720 1.153 NM_138462
ZMYND19
zinc finger, MYND-type containing 19
chr19_+_38154978 1.153 NM_152266
C19orf40
chromosome 19 open reading frame 40
chr6_+_16237264 1.146 NM_013262
MYLIP
myosin regulatory light chain interacting protein
chr1_-_150029529 1.144 NM_001083963
NM_001083964
NM_001083965
NM_006862
TDRKH



tudor and KH domain containing



chr16_+_2419418 1.131 CCNF
cyclin F
chr7_+_98940801 1.126 ZKSCAN5
zinc finger with KRAB and SCAN domains 5
chr1_-_195382189 1.124 NM_018136
ASPM
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr14_-_22825072 1.124 HOMEZ
homeobox and leucine zipper encoding
chr19_+_63482118 1.123 NM_021089
ZNF8
zinc finger protein 8
chr11_+_63710162 1.123 NM_006819
STIP1
stress-induced-phosphoprotein 1
chr6_+_16237300 1.123 MYLIP
myosin regulatory light chain interacting protein
chr17_+_4560680 1.119 ARRB2
arrestin, beta 2
chr1_-_159257595 1.113 NM_016946
F11R
F11 receptor
chr17_+_4560529 1.112 NM_004313
NM_199004
ARRB2

arrestin, beta 2

chr4_-_2233606 1.110 MXD4
MAX dimerization protein 4
chr4_-_1683712 1.110 NM_006527
SLBP
stem-loop binding protein
chr14_-_72430545 1.108 NM_012074
DPF3
D4, zinc and double PHD fingers, family 3
chr17_+_71772982 1.102 FAM100B
family with sequence similarity 100, member B
chr22_-_17546296 1.092 NM_005984
SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr7_-_66404827 1.089 PMS2P4
postmeiotic segregation increased 2 pseudogene 4
chr7_-_73944616 1.089 STAG3L2
stromal antigen 3-like 2
chr20_+_61967094 1.088 TPD52L2
tumor protein D52-like 2
chr15_+_78139018 1.078 ZFAND6
zinc finger, AN1-type domain 6
chr16_-_85908448 1.076 NM_001195124
NM_001195125
LOC100506581

hypothetical LOC100506581

chr7_-_137337318 1.075 CREB3L2
cAMP responsive element binding protein 3-like 2
chr17_-_77411733 1.071 P4HB
prolyl 4-hydroxylase, beta polypeptide
chr7_+_129497572 1.069 NM_014997
KLHDC10
kelch domain containing 10
chr1_+_5975286 1.066 KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr7_-_137337352 1.065 CREB3L2
cAMP responsive element binding protein 3-like 2
chr1_-_159257567 1.063 F11R
F11 receptor
chr22_-_17546276 1.061 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr1_+_144149794 1.056 NM_006472
TXNIP
thioredoxin interacting protein
chr7_-_150305933 1.044 NM_000238
NM_172056
KCNH2

potassium voltage-gated channel, subfamily H (eag-related), member 2

chr7_+_100047877 1.034 NM_001040098
NM_001040099
NM_023948
MOSPD3


motile sperm domain containing 3


chr4_+_38860418 1.031 NM_025132
WDR19
WD repeat domain 19
chr1_+_5975345 1.024 KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr6_-_32253819 1.024 NM_032741
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr14_+_53933422 1.023 NM_001130851
NM_005192
CDKN3

cyclin-dependent kinase inhibitor 3

chr12_-_120725210 1.022 LOC338799
hypothetical LOC338799
chr7_+_66405077 1.020 STAG3L4
stromal antigen 3-like 4
chrX_+_48934831 1.019


chr17_+_56032385 1.014 PPM1D
protein phosphatase, Mg2+/Mn2+ dependent, 1D
chr7_+_66405010 1.008 NM_022906
STAG3L4
stromal antigen 3-like 4
chr7_-_129868059 1.002 NM_018718
TSGA14
testis specific, 14
chr7_+_66405122 0.999 STAG3L4
stromal antigen 3-like 4
chr22_-_17546234 0.994 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr7_+_73944831 0.990 PMS2P5
postmeiotic segregation increased 2 pseudogene 5
chr1_-_148124738 0.988 NM_003528
HIST2H2BE
histone cluster 2, H2be
chr21_+_42946719 0.979 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
PDE9A



















phosphodiesterase 9A



















chr1_-_52116598 0.977 NRD1
nardilysin (N-arginine dibasic convertase)
chr17_-_70797051 0.976 SLC25A19
solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
chr1_-_11245193 0.960 NM_004958
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
chr15_+_86965526 0.959 NM_022767
AEN
apoptosis enhancing nuclease
chr1_-_11245181 0.956 MTOR
mechanistic target of rapamycin (serine/threonine kinase)
chr9_-_37455429 0.955 ZBTB5
zinc finger and BTB domain containing 5
chr19_-_53832381 0.951 NM_001352
DBP
D site of albumin promoter (albumin D-box) binding protein
chr19_-_38154631 0.950 NM_032816
CCDC123
coiled-coil domain containing 123
chr17_+_43374021 0.950 PNPO
pyridoxamine 5'-phosphate oxidase
chr1_-_11245130 0.949 MTOR
mechanistic target of rapamycin (serine/threonine kinase)
chr14_-_103251497 0.947 NM_001100118
NM_001100119
NM_005432
XRCC3


X-ray repair complementing defective repair in Chinese hamster cells 3


chr1_+_148726537 0.946 NM_025150
TARS2
threonyl-tRNA synthetase 2, mitochondrial (putative)
chr1_-_171838802 0.941 NM_178527
SLC9A11
solute carrier family 9, member 11
chr1_+_170017430 0.940 METTL13
methyltransferase like 13
chr22_+_20316968 0.939 NM_152612
CCDC116
coiled-coil domain containing 116
chrX_+_48265107 0.937 NM_006579
EBP
emopamil binding protein (sterol isomerase)
chr1_+_170017452 0.937 METTL13
methyltransferase like 13
chr17_+_58915909 0.936 NM_001178057
NM_152830
ACE

angiotensin I converting enzyme (peptidyl-dipeptidase A) 1

chr1_-_19101603 0.933 NM_003748
NM_170726
ALDH4A1

aldehyde dehydrogenase 4 family, member A1

chr1_-_11245172 0.933 MTOR
mechanistic target of rapamycin (serine/threonine kinase)
chr7_+_98940537 0.930 ZKSCAN5
zinc finger with KRAB and SCAN domains 5
chr19_+_50887580 0.928 NM_001163377
NM_017659
QPCTL

glutaminyl-peptide cyclotransferase-like

chr19_-_6375536 0.925 KHSRP
KH-type splicing regulatory protein
chr6_-_32203971 0.921 NM_001136153
NM_004381
ATF6B

activating transcription factor 6 beta

chr19_+_41298493 0.919 TBCB
tubulin folding cofactor B
chrX_-_48844929 0.919 NM_007075
WDR45
WD repeat domain 45
chr17_+_38576707 0.918 NM_005899
NBR1
neighbor of BRCA1 gene 1
chr7_-_100021658 0.917 LRCH4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr10_-_69267774 0.913 NM_021800
NM_201262
DNAJC12

DnaJ (Hsp40) homolog, subfamily C, member 12

chr1_+_24158887 0.913 NM_017761
PNRC2
proline-rich nuclear receptor coactivator 2
chr11_-_64302440 0.913 SF1
splicing factor 1
chr16_-_45280612 0.912 NM_018206
VPS35
vacuolar protein sorting 35 homolog (S. cerevisiae)
chr19_-_10352212 0.908 NM_003331
TYK2
tyrosine kinase 2
chr1_+_42920889 0.905 YBX1
Y box binding protein 1
chr1_-_112083387 0.897 NM_019099
C1orf183
chromosome 1 open reading frame 183
chr3_-_37009571 0.893


chr1_-_28113817 0.892 NM_002946
RPA2
replication protein A2, 32kDa
chr1_+_24158898 0.891 PNRC2
proline-rich nuclear receptor coactivator 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.97 2.48e-16 GO:0007049 cell cycle
4.45 3.10e-16 GO:0065004 protein-DNA complex assembly
4.31 6.48e-16 GO:0071824 protein-DNA complex subunit organization
1.61 1.23e-15 GO:0090304 nucleic acid metabolic process
4.67 1.26e-15 GO:0006334 nucleosome assembly
1.38 3.09e-15 GO:0044260 cellular macromolecule metabolic process
2.17 8.14e-15 GO:0022403 cell cycle phase
2.06 1.37e-14 GO:0022402 cell cycle process
4.44 1.39e-14 GO:0031497 chromatin assembly
4.32 1.85e-14 GO:0034728 nucleosome organization
2.27 2.57e-14 GO:0000278 mitotic cell cycle
1.50 9.99e-14 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.19 1.60e-13 GO:0051276 chromosome organization
3.70 1.92e-13 GO:0006333 chromatin assembly or disassembly
1.44 3.18e-13 GO:0034641 cellular nitrogen compound metabolic process
3.54 3.77e-13 GO:0071103 DNA conformation change
3.72 1.38e-12 GO:0006323 DNA packaging
1.42 1.54e-12 GO:0006807 nitrogen compound metabolic process
1.26 4.72e-12 GO:0044237 cellular metabolic process
1.63 1.92e-11 GO:0006996 organelle organization
2.27 2.22e-10 GO:0000279 M phase
1.29 4.56e-10 GO:0043170 macromolecule metabolic process
1.23 1.50e-09 GO:0044238 primary metabolic process
2.15 3.10e-09 GO:0006325 chromatin organization
2.45 5.77e-09 GO:0000087 M phase of mitotic cell cycle
1.42 1.34e-08 GO:0009058 biosynthetic process
2.28 1.40e-08 GO:0034622 cellular macromolecular complex assembly
1.42 3.76e-08 GO:0044249 cellular biosynthetic process
1.52 5.53e-08 GO:0016070 RNA metabolic process
1.85 1.04e-07 GO:0065003 macromolecular complex assembly
2.37 1.18e-07 GO:0000280 nuclear division
2.37 1.18e-07 GO:0007067 mitosis
1.41 1.76e-07 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.19 2.29e-07 GO:0008152 metabolic process
1.51 2.39e-07 GO:0034645 cellular macromolecule biosynthetic process
2.01 2.46e-07 GO:0034621 cellular macromolecular complex subunit organization
1.50 2.51e-07 GO:0009059 macromolecule biosynthetic process
2.21 3.04e-07 GO:0051301 cell division
1.91 3.56e-07 GO:0006259 DNA metabolic process
2.30 4.91e-07 GO:0048285 organelle fission
1.73 8.26e-07 GO:0043933 macromolecular complex subunit organization
1.31 8.32e-07 GO:0080090 regulation of primary metabolic process
1.86 8.63e-07 GO:0051726 regulation of cell cycle
2.26 9.02e-07 GO:0051325 interphase
2.54 9.96e-07 GO:0000075 cell cycle checkpoint
2.18 1.04e-06 GO:0010564 regulation of cell cycle process
1.32 1.08e-06 GO:0060255 regulation of macromolecule metabolic process
1.30 1.10e-06 GO:0031323 regulation of cellular metabolic process
2.49 1.35e-06 GO:0071156 regulation of cell cycle arrest
1.38 2.10e-06 GO:0010556 regulation of macromolecule biosynthetic process
2.16 3.06e-06 GO:0006281 DNA repair
2.23 3.17e-06 GO:0051329 interphase of mitotic cell cycle
1.70 5.21e-06 GO:0033554 cellular response to stress
1.39 7.28e-06 GO:0006355 regulation of transcription, DNA-dependent
1.35 8.60e-06 GO:0071842 cellular component organization at cellular level
1.43 9.01e-06 GO:0010467 gene expression
1.35 9.40e-06 GO:0010468 regulation of gene expression
1.34 1.05e-05 GO:0071841 cellular component organization or biogenesis at cellular level
1.38 1.38e-05 GO:0051252 regulation of RNA metabolic process
1.34 2.17e-05 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.33 3.25e-05 GO:0031326 regulation of cellular biosynthetic process
1.85 4.09e-05 GO:0006974 response to DNA damage stimulus
1.26 4.21e-05 GO:0019222 regulation of metabolic process
1.32 4.67e-05 GO:0051171 regulation of nitrogen compound metabolic process
1.33 4.70e-05 GO:0009889 regulation of biosynthetic process
2.68 9.32e-05 GO:0006310 DNA recombination
1.09 1.15e-04 GO:0009987 cellular process
1.51 1.42e-04 GO:0044085 cellular component biogenesis
1.54 1.77e-04 GO:0022607 cellular component assembly
2.89 2.49e-04 GO:0007059 chromosome segregation
4.70 2.73e-04 GO:0006695 cholesterol biosynthetic process
4.81 1.45e-03 GO:0006271 DNA strand elongation involved in DNA replication
1.60 1.78e-03 GO:0071844 cellular component assembly at cellular level
1.55 1.91e-03 GO:0006351 transcription, DNA-dependent
1.24 2.85e-03 GO:0016043 cellular component organization
1.23 3.30e-03 GO:0071840 cellular component organization or biogenesis
1.50 3.58e-03 GO:0032774 RNA biosynthetic process
3.98 3.79e-03 GO:0016126 sterol biosynthetic process
4.49 3.86e-03 GO:0022616 DNA strand elongation
1.62 5.50e-03 GO:0006396 RNA processing
1.68 6.85e-03 GO:0016071 mRNA metabolic process
2.13 7.24e-03 GO:0006457 protein folding
1.79 9.19e-03 GO:0006397 mRNA processing
2.10 1.40e-02 GO:0000375 RNA splicing, via transesterification reactions
2.33 1.52e-02 GO:0051052 regulation of DNA metabolic process
1.87 2.14e-02 GO:0008380 RNA splicing
2.11 3.09e-02 GO:0006260 DNA replication
2.65 3.96e-02 GO:0018196 peptidyl-asparagine modification
2.65 3.96e-02 GO:0018279 protein N-linked glycosylation via asparagine
2.72 4.02e-02 GO:0006275 regulation of DNA replication
2.05 4.50e-02 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.05 4.50e-02 GO:0000398 nuclear mRNA splicing, via spliceosome

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.34 4.68e-47 GO:0043227 membrane-bounded organelle
1.34 2.59e-46 GO:0043231 intracellular membrane-bounded organelle
1.53 2.14e-45 GO:0005634 nucleus
1.30 7.92e-45 GO:0043226 organelle
1.30 1.25e-44 GO:0043229 intracellular organelle
1.23 8.97e-42 GO:0044424 intracellular part
1.22 3.03e-40 GO:0005622 intracellular
2.65 1.32e-24 GO:0005694 chromosome
2.78 1.71e-23 GO:0044427 chromosomal part
1.36 1.98e-21 GO:0044446 intracellular organelle part
1.35 3.07e-21 GO:0044422 organelle part
1.62 1.87e-18 GO:0070013 intracellular organelle lumen
1.63 6.73e-18 GO:0044428 nuclear part
1.60 7.64e-18 GO:0031974 membrane-enclosed lumen
1.60 2.54e-17 GO:0043233 organelle lumen
3.15 1.14e-16 GO:0000785 chromatin
5.34 2.41e-14 GO:0000786 nucleosome
1.62 3.18e-14 GO:0031981 nuclear lumen
4.16 4.80e-13 GO:0032993 protein-DNA complex
1.71 6.97e-13 GO:0005654 nucleoplasm
1.37 2.33e-11 GO:0032991 macromolecular complex
1.41 4.62e-10 GO:0043228 non-membrane-bounded organelle
1.41 4.62e-10 GO:0043232 intracellular non-membrane-bounded organelle
1.16 1.76e-08 GO:0005737 cytoplasm
2.68 2.91e-07 GO:0044454 nuclear chromosome part
1.19 1.63e-06 GO:0044444 cytoplasmic part
2.74 3.56e-06 GO:0000793 condensed chromosome
2.37 4.23e-06 GO:0000228 nuclear chromosome
1.64 5.55e-05 GO:0044451 nucleoplasm part
3.58 1.79e-04 GO:0000794 condensed nuclear chromosome
1.27 2.04e-04 GO:0043234 protein complex
2.46 2.22e-04 GO:0000775 chromosome, centromeric region
1.57 1.42e-03 GO:0015630 microtubule cytoskeleton
2.02 2.19e-03 GO:0016604 nuclear body
1.65 2.46e-03 GO:0030529 ribonucleoprotein complex
1.55 2.47e-03 GO:0044429 mitochondrial part
1.03 1.22e-02 GO:0044464 cell part
1.03 1.26e-02 GO:0005623 cell
1.27 1.51e-02 GO:0005829 cytosol
1.79 1.70e-02 GO:0005874 microtubule
2.78 1.88e-02 GO:0000922 spindle pole
1.32 3.82e-02 GO:0005739 mitochondrion

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.49 8.00e-19 GO:0003676 nucleic acid binding
1.56 1.28e-15 GO:0003677 DNA binding
1.12 6.70e-12 GO:0005488 binding
1.18 1.31e-07 GO:0005515 protein binding
1.61 1.22e-06 GO:0030528 transcription regulator activity
1.53 1.05e-04 GO:0001071 nucleic acid binding transcription factor activity
1.53 1.05e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.52 1.42e-03 GO:0003723 RNA binding
1.52 4.91e-03 GO:0019899 enzyme binding
4.01 9.85e-03 GO:0004003 ATP-dependent DNA helicase activity
1.26 1.10e-02 GO:0000166 nucleotide binding
3.37 1.94e-02 GO:0019888 protein phosphatase regulator activity
3.11 3.02e-02 GO:0019208 phosphatase regulator activity
6.90 3.38e-02 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity